The head and neck collection includes upper aerodigestive tract (UAT) and non-UAT samples.
Most of the samples are of tumor origin, but the collection also includes inflammatory or infectious lesions, and benign tumors.
As of 2018, it includes: 3,862 tissue samples and 632 blood samples, corresponding to 707 patients.
These samples are associated with clinical data, including the clinical history of the patients and their alcohol-smoking status.
For each tissue sample, we store up to 4 lesional tissue fragments and 4 healthy tissue fragments; at -80°C. For each tissue type, one of the fragments is dedicated to a diagnostic use, the others to research use. Additional tissue fragments may be included in paraffin (room temperature storage) and some may be included in the tissue blocks collection (storage at 4°C). The paraffin-embedded tissue blocks can, on request, enable the construction of collections dedicated to targeted pathologies as tissue microarrays (TMA).
Characterization by immunohistochemistry of paraffin-embedded tissue blocks can be performed on request, with a whole range of antibodies.
Plasma and serum are collected from patient blood samples and stored at -80°C. Derivatives are also prepared from the samples: DNA and RNA from healthy and lesional tissues.
Identification of genetic alterations from tissues, blood samples or directly from nucleic acids can be performed on request.
The Biobank Côte d’Azur offers a full range of bioservices to industry, academia and international consortia.
Our policy is to be able to respond to different types of scientific and medical collaborations depending on the needs of applicants and the collaborative and cont[...]