For each patient, up to 4 fragments are collected from the lesion area and the healthy zone and stored at -80°C. For each tissue type, one of the fragments is dedicated to a diagnostic use, the others to research use.
Additional tissue fragments may be included in paraffin (room temperature storage) and some may be included in the tissue block collection (storage at 4°C). The paraffin-embedded tissue blocks can, on request, enable the construction of collections dedicated to targeted pathologies as tissue microarrays (TMA).
Characterization by immunohistochemistry of paraffin-embedded tissue blocks can be performed on request, with a whole range of antibodies.
Plasma and serum are collected from patient blood samples and stored at -80°C. Derivatives are also prepared from the samples: DNA and RNA from healthy and lesional tissues.
Identification of genetic alterations from tissues, blood samples or directly from nucleic acids can be performed on request.