BIOBANKING
Ophtalmology Collection
About
The Ophtalmology Collection
The ophthalmology collection includes specimens from orbital, ocular and conjunctival pathology. It focuses primarily on uveal melanoma, but also includes benign tumours. The collection includes 193 tissue samples and 267 blood samples from 460 patients.
BIOSAMPLE DIVERSITY
The collection includes several types of samples: frozen or paraffin-embedded tissue, biological fluids and derived products (PBMC cells). In addition, the clinical data associated with the samples are enriched with a complete survey and identification of genetic alterations from uveal melanomas is performed. For each tissue sample, we store 1 healthy tissue fragments and up to 4 lesional tissue fragments at -80°C. For each tissue type, one of the fragments is dedicated to diagnostic use, and the others to research use. Additional tissue fragments may be included in paraffin (room temperature storage) and some may be included in the tissue blocks collection (storage at 4°C). The paraffin-embedded tissue blocks can, on request, enable the construction of collections dedicated to targeted pathologies as tissue microarrays (TMA).
Characterization by immunohistochemistry of paraffin-embedded tissue blocks can be performed on request, with a whole range of antibodies
Liquid biopsies collections
or the liquid biopsies of the melanoma collection, plasma, whole blood, are collected from patient blood samples and stored at -80°C.
From the blood samples, PBMC cells are also extracted and stored in liquid nitrogen. We also collect anterior chamber samples for uveal melanoma collection, stored at -80°C.
Tissue sample
Blood derivatives details + tissue samples associated with their pathologies (nb of samples and %)
Our
Services
Sample Transfer
The Biobank Côte d’Azur offers a full range of bioservices to industry, academia and international consortia.
Our policy is to be able to respond to different types of scientific and medical collaborations depending on the needs of applicants and the collaborative and cont[...]
Platforms
The Biobank Côte d’Azur collects human samples associated with various organs and pathologies.
For each of these, we collect numerous biosamples such as tissue fragments (lesional and peri-lesional tissues), biofluids and derived bioproducts. Each sample is associa[...]